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Updated: Jun 18, 2026

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
Published on: March 15, 2024
[Recurrent massive bloody pleural effusion caused by pancreatic pleural fistula in a case]
Hui-min Li1, Shun-ying Zhao, Jin Zhou
1Department of Pediatric Internal Medicine, Beijing Children's Hospital Affiliated to Capital Medical University, Be4iing 100045, China.
Insights
Pediatric pancreatic pleural fistula often presents with respiratory symptoms and bloody pleural effusion. Elevated amylase in pleural fluid is a key diagnostic clue, guiding treatment with ERCP if conservative measures fail.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Pulmonology
Background:
- Pancreatic pleural fistula is a rare condition where a connection forms between the pancreas and the pleural space.
- Early diagnosis and treatment are crucial, but often delayed due to non-specific initial symptoms.
Observation:
- A 4-year-old boy presented with a month of fever, cough, and chest pain, exhibiting massive bloody pleural effusion.
- Initial abdominal examination was unremarkable, but pancreatic echo was abnormal on ultrasound.
- Significantly elevated amylase levels were found in both blood (495 U/L) and pleural fluid (35,938 U/L).
Findings:
- Thoracic surgical exploration revealed a fistulous tract connecting the thoracic cavity to the pancreas.
- The child was successfully treated with total parenteral nutrition, somatostatin infusion, and endoscopic retrograde cholangiopancreatography (ERCP)-guided pancreatic duct stenting.
Implications:
- Respiratory symptoms and bloody pleural effusion in children can indicate pancreatic pleural fistula.
- High amylase levels in pleural fluid are a critical diagnostic marker.
- ERCP is a valuable tool for both diagnosis and treatment when conservative management is insufficient.
Objective:
To introduce the early clinical features and the main points of diagnosis and treatment of children with pancreatic pleural fistula presenting massive bloody pleural effusion.
Method:
The clinical data of symptoms, signs, laboratory examination, diagnosis and treatment methods of pancreatic pleural fistula in a child are presented.
Result:
A 4-year-old boy presented with one month history of intermittent fever, cough, chest tightness and chest pain. His pleural effusion collected from three thoracic closed drainage was hemorrhagic. He had no positive abdominal signs. His abdominal B-mode ultrasonography showed rough pancreatic echo. The levels of amylase in blood and pleural fluid were 495 U/L and 35 938 U/L, respectively. There was a fistulous tract from the thoracic cavity leading to the pancreas at thoracic surgical exploration. The child was cured by total parenteral nutrition, intravenous infusion of somatostatin and a stent placed in the pancreatic duct by endoscopic retrograde cholangiopancreatography (ERCP).
Conclusion:
The child with pancreatic pleural fistula in early stage mainly present respiratory symptoms and lack abdominal symptoms, so the diagnosis and treatment is often delayed. Significant increase of pancreatic amylase level in pleural effusion can be an important clue and basis for the diagnosis. If conservative therapy fails, the examination and treatment with ERCP should be considered.
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