[Recurrent massive bloody pleural effusion caused by pancreatic pleural fistula in a case]

Hui-min Li1, Shun-ying Zhao, Jin Zhou

  • 1Department of Pediatric Internal Medicine, Beijing Children's Hospital Affiliated to Capital Medical University, Be4iing 100045, China.

Insights

Pediatric pancreatic pleural fistula often presents with respiratory symptoms and bloody pleural effusion. Elevated amylase in pleural fluid is a key diagnostic clue, guiding treatment with ERCP if conservative measures fail.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Pulmonology

Background:

  • Pancreatic pleural fistula is a rare condition where a connection forms between the pancreas and the pleural space.
  • Early diagnosis and treatment are crucial, but often delayed due to non-specific initial symptoms.

Observation:

  • A 4-year-old boy presented with a month of fever, cough, and chest pain, exhibiting massive bloody pleural effusion.
  • Initial abdominal examination was unremarkable, but pancreatic echo was abnormal on ultrasound.
  • Significantly elevated amylase levels were found in both blood (495 U/L) and pleural fluid (35,938 U/L).

Findings:

  • Thoracic surgical exploration revealed a fistulous tract connecting the thoracic cavity to the pancreas.
  • The child was successfully treated with total parenteral nutrition, somatostatin infusion, and endoscopic retrograde cholangiopancreatography (ERCP)-guided pancreatic duct stenting.

Implications:

  • Respiratory symptoms and bloody pleural effusion in children can indicate pancreatic pleural fistula.
  • High amylase levels in pleural fluid are a critical diagnostic marker.
  • ERCP is a valuable tool for both diagnosis and treatment when conservative management is insufficient.
Abstract

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