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Updated: Jun 18, 2026

An Efficient In Vitro Transposition Method by a Transcriptionally Regulated Sleeping Beauty System Packaged into an Integration Defective Lentiviral Vector
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An Efficient In Vitro Transposition Method by a Transcriptionally Regulated Sleeping Beauty System Packaged into an Integration Defective Lentiviral Vector

Published on: January 12, 2018

[Development and therapeutic application of transposon-based vectors].

Hideyuki Nakanishi1, Yuriko Higuchi, Shigeru Kawakami

  • 1Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.

Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan
|December 3, 2009
PubMed
Summary

Transposons, mobile genetic elements, offer efficient gene integration into chromosomes for gene therapy. These systems show therapeutic potential for various diseases, with ongoing research addressing challenges like insertional mutagenesis.

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