Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mortality and graft loss in face transplantation: lessons from two decades of experience.

Clinical transplantation and research·2026
Same author

Comparison Of Effects Of Stromal Vascular Fraction And Nano-Fat Applications On Skin Quality And Photoaging.

Plastic and reconstructive surgery·2026
Same author

Lymphatic Recovery and Clinical Implications in Hand Allotransplantation: Insights From Indocyanine Green Lymphangiography.

Cureus·2026
Same author

Nail abnormalities in upper extremity transplantation: Perspectives and insights from systemic diseases and organ transplantation.

World journal of transplantation·2026
Same author

Bone complications after hand and face transplantation: Mechanisms and management.

JPRAS open·2026
Same author

Correction of Mandibular Asymmetry With Bilateral Asymmetric Custom-Made 3D Implant.

The Journal of craniofacial surgery·2026
Same journal

"Inferior Repositioning of the High-Riding Nipple Using a Parenchymal-Based Flap".

Plastic and reconstructive surgery·2026
Same journal

A Four-Step Strategy for the Treatment of Facial Rhytids: A Focus on Upper Facial Wrinkles.

Plastic and reconstructive surgery·2026
Same journal

Evaluating Long-Term Retention of Fresh-Frozen Costal Cartilage Allograft in An Animal Model.

Plastic and reconstructive surgery·2026
Same journal

Manual extrusion of fat granules for primary thinning of a bulky flap.

Plastic and reconstructive surgery·2026
Same journal

"Impact of regional surgeon competition on use and costs of carpal tunnel releases".

Plastic and reconstructive surgery·2026
Same journal

Prevention of Tendon Adhesion and Preservation of Healing Strength Using a Hydrophobically Modified Alaska Pollock Gelatin Sheet.

Plastic and reconstructive surgery·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

Procurement for a Vascularized and Reinnervated Abdominal Wall Allotransplantation
09:30

Procurement for a Vascularized and Reinnervated Abdominal Wall Allotransplantation

Published on: July 18, 2025

Composite tissue allotransplantation.

Maria Z Siemionow1, Yalcin Kulahci, Mehmet Bozkurt

  • 1Cleveland, Ohio; and Istanbul and Diyarbakır, Turkey From the Department of Plastic Surgery, Cleveland Clinic; Department of Plastic and Reconstructive Surgery and Burn Unit, Gülhane Military Medical Academy and Medical Faculty, Haydarpasa Training Hospital; and Dicle University Department of Plastic and Reconstructive Surgery.

Plastic and Reconstructive Surgery
|December 3, 2009
PubMed
Summary
This summary is machine-generated.

Composite tissue allotransplantation offers reconstructive solutions for complex injuries. This review covers experimental models and clinical uses of composite tissue allotransplantation, highlighting its potential in regenerative medicine.

More Related Videos

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
09:43

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
08:11

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation

Published on: June 13, 2025

Related Experiment Videos

Last Updated: Jun 18, 2026

Procurement for a Vascularized and Reinnervated Abdominal Wall Allotransplantation
09:30

Procurement for a Vascularized and Reinnervated Abdominal Wall Allotransplantation

Published on: July 18, 2025

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
09:43

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
08:11

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation

Published on: June 13, 2025

Area of Science:

  • Regenerative Medicine
  • Transplantation Immunology
  • Surgical Reconstruction

Background:

  • Composite tissue allotransplantation (CTA) is a promising treatment for extensive tissue loss from tumors, trauma, or burns.
  • CTA involves transplanting heterogeneous tissues (skin, muscle, bone, nerves, etc.), each with unique antigenicity.
  • The diverse antigens in CTA can provoke a stronger immune response than solid organ transplants.

Purpose of the Study:

  • To review experimental models of composite tissue allotransplantation.
  • To outline current clinical applications of composite tissue allotransplantation.
  • To discuss the immunological challenges and potential of CTA.

Main Methods:

  • Literature review of experimental models in CTA.
  • Analysis of clinical case studies and outcomes in CTA.
  • Examination of immunological responses in composite tissue allotransplantation.

Main Results:

  • Various experimental models have been developed to study CTA.
  • CTA has demonstrated clinical success in reconstructive surgery.
  • Understanding antigenicity is crucial for managing immune responses in CTA.

Conclusions:

  • Composite tissue allotransplantation is a viable option for complex reconstructions.
  • Further research into managing immune responses is essential for CTA success.
  • CTA holds significant potential for advancing reconstructive surgery and regenerative medicine.