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Updated: Jun 18, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
Ocular tilt reaction as a delayed complication of deep brain stimulation for Parkinson disease
Santiago Ortiz-Pérez1, Bernardo Sánchez-Dalmau, Juan Molina
1Institut Clínic d'Oftalmologìa, Servicio de Neurocirugía, Hospital Clínic i Provincial, Barcelona, Spain. san.ortiz@gmail.com
Abstract:
A 57-year-old-man treated with deep brain stimulation (DBS) of both subthalamic nuclei for advanced Parkinson disease developed a brain hemorrhage near the site of one of the DBS electrodes 9 months after implantation. The hemorrhage caused vertical diplopia from skew deviation. Examination also disclosed evidence of ipsiversive binocular torsion and a right head tilt, constituting an ocular tilt reaction (OTR). Fourteen months later, he was still symptomatic from diplopia. An OTR has not previously been reported as a delayed complication of DBS.
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