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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Kidney Structure01:45

Kidney Structure

The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.

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De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2010
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[Concept to improve adherence in adolescents following renal transplantation: vision or reality?].

Der Urologe. Ausg. A·2009
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Superior long-term graft function and better growth of grafts in children receiving kidneys from paediatric compared with adult donors.

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Kidney transplantation without prior dialysis in children: the Eurotransplant experience.

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Related Experiment Video

Updated: Jun 18, 2026

Murine Kidney Transplant Technique
08:58

Murine Kidney Transplant Technique

Published on: October 20, 2015

[Pediatric kidney transplantation].

G Offner1

  • 1Pädiatrische Nephrologie, Medizinische Hochschule, Hannover, Deutschland. offner.gisela@t-online.de

Der Urologe. Ausg. A
|December 3, 2009
PubMed
Summary
This summary is machine-generated.

Kidney transplantation is a key treatment for children with end-stage kidney disease. The goal is to improve survival and ensure normal growth and development by minimizing immunosuppression side effects.

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Last Updated: Jun 18, 2026

Murine Kidney Transplant Technique
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Area of Science:

  • Pediatric Nephrology
  • Transplant Surgery
  • Immunosuppression Therapy

Context:

  • End-stage renal disease (ESRD) in children necessitates kidney transplantation.
  • Assessing post-transplant outcomes extends beyond graft and patient survival.
  • Evaluating growth and developmental trajectories is crucial for pediatric recipients.

Purpose:

  • To define treatment strategies for pediatric kidney transplantation.
  • To minimize adverse effects associated with immunosuppressive medications.
  • To facilitate optimal growth and development in pediatric renal transplant recipients.

Summary:

  • Kidney transplantation is the primary treatment for children facing terminal renal failure.
  • Beyond survival rates, the focus is on the child's overall condition, including growth and development.
  • Treatment aims to reduce immunosuppression side effects for better long-term outcomes.

Impact:

  • Informs clinical practice for pediatric renal transplant management.
  • Highlights the importance of holistic patient care in pediatric transplantation.
  • Aims to improve the quality of life for children post-kidney transplant.