Breast metastasis from nasopharyngeal carcinoma

The first two cases of breast metastases from anaplastic carcinoma of the nasopharynx are presented. In both cases the breast metastasis was solitary, but there was no delay in confirming their metastatic nature since both lesions manifested after the documentation of disseminated disease. The difference in histology, since 99% of our nasopharyngeal carcinoma patients have anaplastic carcinoma of poorly differentiated carcinoma subtype, makes it easy to differentiate them from primary breast cancer by cytology or histology.