Related Experiment Video
Updated: Jun 18, 2026

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
Published on: December 1, 2023
The effects of low- and high-glycemic index foods on high-intensity intermittent exercise
Jonathan P Little1, Philip D Chilibeck, Dawn Ciona
1College of Kinesiology, University of Saskatchewan, Saskatoon, SK, Canada.
Unlabelled:
The glycemic index (GI) of a preexercise meal may affect substrate utilization and performance during continuous exercise.
Purpose:
To examine the effects of low- and high-GI foods on metabolism and performance during high-intensity, intermittent exercise.
Methods:
Seven male athletes participated in three experimental trials (low-GI, high-GI, and fasted control) separated by approximately 7 days. Foods were consumed 3 h before (approximately 1.3 g x kg(-1) carbohydrate) and halfway through (approximately 0.2 g x kg(-1) carbohydrate) 90 min of intermittent treadmill running designed to simulate the activity pattern of soccer. Expired gas was collected during exercise to estimate substrate oxidation. Performance was assessed by the distance covered on five 1-min sprints during the last 15 min of exercise.
Results:
Respiratory exchange ratio was higher and fat oxidation lower during exercise in the high-GI condition compared with fasting (P < .05). The mean difference in total distance covered on the repeated sprint test between low GI and fasting (247 m; 90% confidence limits +/-352 m) represented an 81% (likely, probable) chance that the low-GI condition improved performance over fasting. The mean difference between high GI and fasted control (223 m; +/- 385 m) represented a 76% (likely, probable) chance of improved performance. There were no differences between low and high GI.
Conclusions:
When compared with fasting, both low- and high-GI foods consumed 3 h before and halfway through prolonged, high-intensity intermittent exercise improved repeated sprint performance. High-GI foods impaired fat oxidation during exercise but the GI did not appear to influence high-intensity, intermittent exercise performance.
Related Concept Videos
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
Hypoglycemia
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
Oral Hypoglycemic Agents: α-Glucosidase Inhibitors
Acarbose and miglitol are typically...
Metabolic States of the Body: The Postabsorptive State
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Hypoglycemia and Glucagon

