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Updated: Jun 18, 2026

Developing a Clinically Relevant Hemorrhagic Shock Model in Rats
Published on: March 22, 2024
[Application of Rheosorbilactum in the therapy of traumatic shock: comparative study]
Abstract:
The authors have studied influence of infusion of 800 ml RHEOSORBILACTUM, 500 ml VENOFUNDIN and 800 ml of 0,9% isotonic solution of sodium chloride with speed of 50-55 ml/mines on hemostasis, the maintenance of a liquid in the thorax, hemodynamic parameters in 60 patients with traumatic shock. It was revealed that the use of investigated volume of RHEOSORBILACTUM increases reliably (P<0,05) oxygen delivery for the account of the expressed haemodynamic effect which duration is less than during the use of VENOFUNDIN. It was revealed also that RHEOSORBILACTUM increases reliably (P<0,05) quantity of liquid in the thorax without an considerable difference with other investigated medications. There was no influence of RHEOSORBILACTUM on time of trombus formation tests--prothrombin time, the international normalized index, activated partial thromboplastin time.
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