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Generation of Induced Pluripotent Stem Cells from Turner Syndrome (45XO) Fetal Cells for Downstream Modelling of Neurological Deficits Associated with the Syndrome
09:39

Generation of Induced Pluripotent Stem Cells from Turner Syndrome (45XO) Fetal Cells for Downstream Modelling of Neurological Deficits Associated with the Syndrome

Published on: December 4, 2021

Management of cardiovascular disease in Turner syndrome

Joshua Thomas1, Anji T Yetman

  • 1University of Utah, Salt Lake City, UT 84105, USA.

Expert Review of Cardiovascular Therapy
|December 4, 2009
PubMed

Insights

Patients with Turner syndrome need lifelong heart monitoring due to associated cardiovascular conditions. This review covers cardiac issues and care guidelines for Turner syndrome patients from infancy to adulthood.

Area of Science:

  • Cardiology
  • Genetics
  • Pediatrics

Background:

  • Turner syndrome is a genetic condition affecting females, often associated with significant cardiovascular comorbidities.
  • Lifelong cardiac surveillance is essential for individuals with Turner syndrome due to a high prevalence of heart abnormalities.

Purpose of the Study:

  • To review the current understanding of cardiovascular pathology in Turner syndrome.
  • To provide comprehensive cardiac care recommendations for Turner syndrome patients throughout their lives.

Main Methods:

  • Literature review of existing studies on Turner syndrome and cardiovascular disease.
  • Synthesis of current clinical guidelines and expert consensus.

Main Results:

  • Detailed overview of common cardiovascular abnormalities in Turner syndrome, including aortic dilatation and bicuspid aortic valve.
  • Identification of critical monitoring points and intervention strategies based on age and specific cardiac findings.

Conclusions:

  • Early and continuous cardiac evaluation is crucial for managing Turner syndrome patients.
  • Adherence to recommended surveillance protocols can improve long-term cardiovascular outcomes in Turner syndrome.

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