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Detection of human interchromosomal trans-splicing in sequence databanks

Roberto Hirochi Herai1, Michel E Beleza Yamagishi

  • 1Genetics and Molecular Biology Department, Biology Institute, State University of Campinas, 13083-862 Campinas, SP, Brazil. rherai@cnptia.embrapa.br

Briefings in Bioinformatics
|December 4, 2009
PubMed
Summary

Researchers discovered 16 hybrid messenger RNAs (mRNAs) in human sequence databases, suggesting trans-splicing is more common than previously thought. This finding challenges traditional splice site rules and points to novel splicing mechanisms in normal tissues.

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