Detection of ischemic electroencephalography changes during carotid endarterectomy using synchronization likelihood...

Area of Science:

• Neuroscience
• Anesthesiology
• Critical Care Medicine

Background:

• Cerebral ischemia detection lacks effective real-time tools in intensive care units.
• Synchronization Likelihood (SL) analysis of electroencephalography (EEG) shows promise for online seizure detection.

Purpose of the Study:

• To evaluate the utility of SL analysis for detecting cerebral ischemia during carotid endarterectomy.

Main Methods:

• EEG data from 143 carotid endarterectomy procedures were analyzed using SL.
• EEG data were compared before and after carotid artery clamping under isoflurane and propofol anesthesia.
• Cerebral ischemia was defined using EEG variables.

Main Results:

• Overall, 27% of patients developed ischemia.
• In the isoflurane group with ischemia, mean SL slightly decreased post-clamping (P=0.06).
• In the propofol group with ischemia, mean SL remained stable (P=0.87).
• Patients without ischemia showed increased mean SL values post-clamping in both anesthesia groups.

Conclusions:

• No significant changes in mean SL were observed with cerebral ischemia development under either anesthesia.
• SL analysis appears unsuitable for detecting cerebral ischemia in anesthetized patients.