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Pigmented villonodular synovitis of thoracic facet joint presenting as rapidly progressive paraplegia
Leticia del Carmen Baena-Ocampo1, Luis M Rosales Olivares, Norma Marín Arriaga
1Department of Pathology, Instituto Nacional de Rehabilitación, Mexico City, México.
Abstract:
Pigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovial membrane of uncertain etiology. It commonly affects synovial joints of the appendicular skeleton and rarely affects the spine. We present the case of a young man presenting with a rapidly progressive myelopathy due to spinal cord compression by PVNS arising from a thoracic facet joint, which finally resulted in paraplegia.The spinal location of PVNS has been seldom emphasized in the rheumatologic literature. PVNS should be considered as a possible cause of soft tissue masses arising from the facet joints, with variable degrees of nerve root or spinal cord compression.
Insights
Pigmented villonodular synovitis (PVNS) is a rare spinal condition. This case highlights PVNS in a thoracic facet joint causing myelopathy and paraplegia, emphasizing its potential for spinal cord compression.
Area of Science:
- Rheumatology
- Neurology
- Orthopedic Surgery
Background:
- Pigmented villonodular synovitis (PVNS) is a rare, benign neoplastic proliferation of the synovial membrane.
- While commonly affecting appendicular joints, spinal involvement is infrequent.
- The etiology of PVNS remains uncertain, contributing to diagnostic challenges.
Observation:
- A young male presented with rapidly progressive myelopathy leading to paraplegia.
- The cause was identified as PVNS originating from a thoracic facet joint.
- This spinal PVNS led to significant spinal cord compression.
Findings:
- Spinal PVNS, though rare, can manifest as a soft tissue mass in facet joints.
- This mass can cause severe neurological deficits, including nerve root or spinal cord compression.
- The case underscores the potential for PVNS to cause progressive myelopathy.
Implications:
- PVNS should be considered in the differential diagnosis of spinal soft tissue masses, particularly those causing neurological compromise.
- Early recognition and diagnosis of spinal PVNS are crucial for timely intervention and management.
- Further research into the spinal manifestations of PVNS may improve patient outcomes.
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