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Updated: Jun 18, 2026

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
Published on: August 28, 2015
Surface segregation assessment in poly(epsilon-caprolactone)-poly(ethylene glycol) multiblock copolymer films
Stefania Cometa1, Federica Chiellini, Irene Bartolozzi
1Laboratory of Bioactive Polymeric Materials for Biomedical and Environmental Applications (BIOlab) UdR-INSTM, Department of Chemistry and Industrial Chemistry, University of Pisa, Via Vecchia Livornese 1291, 56010, S. Piero a Grado, Pisa, Italy.
Abstract:
The ability to predict the in vivo performance of multiblock-copolymer-based biomaterials is crucial for their applicability in the biomedical field. In this work, XPS analysis of PCL-PEG copolymers was carried out, as well as morphological and wettability evaluations by SEM and CA measurements, respectively. XPS analysis on films equilibrated in PBS demonstrated a further enrichment in the PEG component on the surface. Copolymer films obtained by casting using different solvents showed a dependence in segregation according to the solvent employed. Cell adhesion tests demonstrated the importance of copolymer segregation and rearrangement in a wet environment, with a dependence of these phenomena on the copolymer molecular weight.
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