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Updated: Jun 18, 2026

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
Published on: May 27, 2022
[The detection of sera S100B and NO of patients with brain injury]
Ke Su1, Deng-yuan Song, You-jiang Chen
1Department of Neurosurgery, Shenzhen Fuyong Hospital, China.
Objective:
To explore the changes of sera S100B and NO and their significance of patients with brain injury.
Method:
We detected sera S100B and NO level of 30 healthy persons and 108 cases with brain injury by ELISA and method.
Results:
The sera S100B level of patient group was increased after 12 h brain injury,and sera NO concentrations of serve type were significantly high than control group, P < 0.01. NO concentrations of serve type, middle type and minor type were significantly high than control group, middle type and minor type group. P < 0.05, However, sera NO level of middle type and minor type group of brain injury had no significance than control group, P > 0.05.
Conclusion:
Sera S100B examinations can be indices as diagnosis of early brain injury.

