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Updated: Jun 18, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Migraine and functional impairment.

Jan Lewis Brandes¹

¹Saint Thomas Health Services, Nashville Neuroscience Group, Departmentof Neurology, Vanderbilt University School of Medicine,300 Twentieth Ave. N, Suite 603, Nashville, TN 37203, USA. jbrandes@nashvilleneuroscience.com

|December 5, 2009

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Migraine significantly impacts daily life, causing disability between attacks. Understanding this interictal burden helps physicians tailor treatments for better patient outcomes.

Area of Science:

Neurology
Public Health

Background:

Migraine is a primary cause of global disability, severely limiting daily activities for many.
Beyond acute attacks, the interictal burden (worry, anticipation) affects social, family, and work life.

Purpose of the Study:

To enhance physician understanding of the full scope of functional impairment caused by migraine.
To highlight the importance of assessing interictal burden for effective treatment selection.

Main Methods:

Review of literature on migraine-related functional impairment.
Description of assessment tools like the Migraine Disability Assessment questionnaire.
Summary of studies on quality of life and treatment effects.

Main Results:

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Last Updated: Jun 18, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Migraine's interictal burden leads to significant limitations in daily functioning.

Various instruments effectively measure migraine-related functional impairment.

Preventive treatments show potential to improve functional impairment.

Conclusions:

Assessing interictal burden is crucial for personalized migraine management.
Physician awareness and appropriate assessment tools can optimize patient care and treatment efficacy.