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Updated: Jun 18, 2026

Multimodal Cross-Device and Marker-Free Co-Registration of Preclinical Imaging Modalities
Published on: October 27, 2023
SPECT/CT in imaging foot and ankle pathology-the demise of other coregistration techniques
Hosahalli K Mohan1, Gopinath Gnanasegaran, Sanjay Vijayanathan
1Department of Nuclear Medicine, Guy's and St. Thomas' Hospitals, NHS Trust, London, United Kingdom. mohanhk@hotmail.com
Abstract:
Disorders of the ankle and foot are common and given the complex anatomy and function of the foot, they present a significant clinical challenge. Imaging plays a crucial role in the management of these patients, with multiple imaging options available to the clinician. The American College of radiology has set the appropriateness criteria for the use of the available investigating modalities in the management of foot and ankle pathologies. These are broadly classified into anatomical and functional imaging modalities. Recently, single-photon emission computed tomography and/or computed tomography scanners, which can elegantly combine functional and anatomical images have been introduced, promising an exciting and important development. This review describes our clinical experience with single-photon emission computed tomography and/or computed tomography and discusses potential applications of these techniques.
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