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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Cardiac resynchronization therapy utilization for heart failure: findings from IMPROVE HF
Anne B Curtis1, Clyde W Yancy, Nancy M Albert
1University of South Florida College of Medicine, Tampa, FL 33612, USA. acurtis@health.usf.edu
Insights
Cardiac resynchronization therapy (CRT) is underutilized in eligible heart failure patients, with significant practice variations. Age, insurance, QRS duration, and location impact CRT device utilization.
Area of Science:
- Cardiology
- Heart Failure Management
- Medical Device Utilization
Background:
- Cardiac resynchronization therapy (CRT) is effective for systolic heart failure (HF).
- CRT utilization rates and influencing factors in outpatient cardiology practices remain understudied.
Purpose of the Study:
- To investigate CRT treatment rates among eligible heart failure patients.
- To identify patient and practice characteristics associated with CRT utilization.
Main Methods:
- Prospective cohort study (IMPROVE HF) of 15,381 chronic HF patients in US outpatient cardiology practices.
- Baseline data collected via chart review (May 2005-June 2007).
- Multivariable analyses identified predictors of CRT use in 1,373 eligible patients.
Main Results:
- 38.8% of eligible patients received a CRT device; 84.1% were CRT-defibrillators.
- Wide practice variation in CRT use (11.1% to 53.4%).
- Higher CRT utilization associated with patient age, insurance, longer QRS duration, and practice location.
Conclusions:
- CRT is underutilized despite guideline recommendations.
- Significant variations in CRT use exist, linked to patient demographics and practice location.
- Practice-specific initiatives may be needed to improve CRT utilization.
Background:
Cardiac resynchronization therapy (CRT) has established efficacy for patients with systolic heart failure (HF). Treatment rates and factors associated with CRT utilization among eligible patients in outpatient cardiology practices have not been well studied.
Methods:
IMPROVE HF is a prospective cohort study designed to characterize current management of patients with chronic HF and left ventricular ejection fraction
Results:
A total of 1,373 patients were eligible for CRT based on current guideline criteria, and 533 (38.8%) received a CRT device, with 84.1% of these treated with a CRT-defibrillator. Cardiac resynchronization therapy use varied widely among practices, with 11.1% at the 25th percentile and 53.4% at the 75th percentile. Patient age, insurance, longer QRS duration, and practice location were independently associated with higher CRT utilization rates among eligible patients, whereas sex, HF etiology, and other clinical and laboratory parameters were not.
Conclusions:
Despite being evidence based and guideline recommended, CRT is underutilized in eligible patients with significant variations associated with age, insurance, QRS duration, and geographic location of practices. Practice-specific performance improvement initiatives may be needed to reduce variations in use of CRT for eligible patients.
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