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Updated: Jun 18, 2026

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
Published on: March 5, 2018
Is there a role for maintenance therapy in acute myeloid leukaemia?
1Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. mbaer@umm.edu
Abstract:
Maintenance therapy is not part of current standard treatment for acute myeloid leukaemia (AML). However, in other leukaemias, maintenance therapy is used to prolong responses and increase the cure rate. While maintenance chemotherapy has not been shown to improve outcome in AML, several other maintenance strategies are currently being tested in this disease, including immunotherapy, demethylating agents and targeted therapies. While maintenance chemotherapy does not appear to have a role in AML curative therapy, the novel maintenance strategies currently being tested appear promising and warrant further study.
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