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Related Concept Videos

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
Drug Products: Biologics, Biosimilars and Interchangeables01:28

Drug Products: Biologics, Biosimilars and Interchangeables

Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.

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Related Experiment Video

Updated: Jun 18, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
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Developing products for personalized medicine: NIH Research Tools Policy applications.

Ranjan Gupta, Jp Kim, Jack Spiegel

    Personalized Medicine
    |September 30, 2011
    PubMed
    Summary

    Academic and industrial innovators need rapid access to research tools for personalized medicine development. The National Institutes of Health (NIH) is implementing policies to speed up the sharing of essential research tools and resources.

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    Published on: April 4, 2018

    Area of Science:

    • Biomedical research
    • Translational science
    • Drug discovery

    Background:

    • Personalized medicine development requires advanced research tools and reagents.
    • Delays in accessing these tools can hinder the creation of customized diagnostics and therapeutics.
    • Many patients do not benefit from traditional treatments, highlighting the need for personalized approaches.

    Purpose of the Study:

    • To address the need for accelerated development of personalized medicine products.
    • To streamline access to state-of-the-art research tools and reagents for innovators.
    • To implement policies facilitating the exchange of research tools and resources.

    Main Methods:

    • Review of current National Institutes of Health (NIH) funding agreements.
    • Analysis of NIH's internal research programs and policies.
    • Development of new policies to facilitate resource exchange.

    Main Results:

    • NIH is actively revising its policies to promote faster sharing of research tools.
    • New internal programs are being established to support resource exchange.
    • These initiatives aim to remove unreasonable restrictions and delays.

    Conclusions:

    • Facilitating the exchange of research tools is crucial for advancing personalized medicine.
    • NIH's policy changes are expected to accelerate the development of innovative diagnostics and therapeutics.
    • These efforts will ultimately benefit patients who need tailored treatment options.