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Structure and expression of canary myc family genes
R G Collum1, D F Clayton, F W Alt
1Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, New York, New York 10032.
Molecular and Cellular Biology
|March 1, 1991
Abstract:
We found that the canary N-myc gene is highly related to mammalian N-myc genes in both the protein-coding region and the long 3' untranslated region. Examined coding regions of the canary c-myc gene were also highly related to their mammalian counterparts, but in contrast to N-myc, the canary and mammalian c-myc genes were quite divergent in their 3' untranslated regions. We readily detected N-myc and c-myc expression in the adult canary brain and found N-myc expression both at sites of proliferating neuronal precursors and in mature neurons.