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Updated: Jun 18, 2026

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa
13:40

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa

Published on: February 17, 2014

Multidrug efflux pumps: drug binding--gates or cavity?

Emily Crowley1, Richard Callaghan

  • 1Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK.

The FEBS Journal
|December 8, 2009
PubMed
Summary

Understanding the drug-binding sites of ABCB1 (ATP-binding cassette B1) is crucial for cancer drug development. This review explores strategies to identify these sites, aiding in overcoming chemotherapy resistance.

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