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Updated: Jun 18, 2026
05:07
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Localized early mesenteric Castleman's disease presenting as recurrent intestinal obstruction: a case report
Dina El Demellawy1, Chaturika Herath, Francoise Truong
1Department of Pathology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada. dina_demellawy@oslerhc.org
Diagnostic Pathology
|December 8, 2009
Summary
Primary mesenteric tumors are rare, often mesenchymal. This case highlights localized Castleman
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Primary mesenteric neoplasms are rare, typically mesenchymal (e.g., desmoid tumor, lipoma, liposarcoma, fibrosarcoma).
- Metastatic carcinomas and lymphoma are more frequent mesenteric malignancies.
- Mesenteric tumors can present with varied clinical symptoms, including intestinal obstruction.
Purpose of the Study:
- To report a rare case of localized mesenteric Castleman's disease.
- To emphasize the importance of considering Castleman's disease in the differential diagnosis of mesenteric tumors.
- To discuss the clinical and radiological presentation mimicking lymphoma.
Main Methods:
- Case report of a patient with intestinal obstruction due to a mesenteric mass.
- Review of clinical presentation, radiological findings (CT scan), and histopathological examination.
- Differential diagnosis considerations for mesenteric tumors.
Main Results:
- A rare case of localized Castleman's disease was identified in the mesentery.
- Clinical and radiological findings were initially suggestive of lymphoma.
- The patient presented with symptoms of intestinal obstruction.
Conclusions:
- Localized mesenteric Castleman's disease is an uncommon entity that must be included in the differential diagnosis of mesenteric tumors.
- Castleman's disease should be considered, especially in younger patients without a history of other tumors, abnormal blood work, or splenomegaly.
- Accurate diagnosis is crucial for appropriate management and patient outcomes.
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