Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Detection of severe hemophilia A during neonatal screening].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2017
Same author

[Congenital neuromuscular diseases with neonatal respiratory failure excluding myotonic dystrophy type 1 and infantile spinal muscular atrophy. Diagnosis strategy according to a 19-child series].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2016
Same author

[Postnatal cytomegalovirus infection in preterm infants: the role of breast milk].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2014
Same author

[GACI syndrome: a case report with a neonatal beginning].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2014
Same author

[Severe neurological forms of influenza in children: report on three cases of severe encephalitis in France].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2014
Same author

[Necrotizing enterocolitis: what role is played by cytomegalovirus?].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2014
Same journal

Family experiences of paediatric palliative care during hospital-at-home: a systematic review.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Knowledge of maternity caregivers on vaccination BCG recommendations and circuits.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

"CRANIOQUALITY study: Quality of life in children with non-syndromic craniosynostosis after surgery".

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Chronological evolution of brain imaging of hemiconvulsion-hemiplegia-epilepsy from 5 cases in Mayotte island.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Point-of-care capillary blood ketone testing to predict the need for intravenous or nasogastric tube rehydration in children with acute gastroenteritis.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
Same journal

Transition practices of patients with inflammatory bowel disease from pediatric to adult healthcare systems. Results from a national survey.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

[Malignant pertussis: 3 case reports].

L Berthomieu1, B Boumahni, K Jamal Bey

  • 1Service de réanimation néonatale et pédiatrique, groupe hospitalier Sud-Réunion, 97410 Saint-Pierre, Réunion, France. lionel.berthomieu@voila.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|December 8, 2009
PubMed
Summary
This summary is machine-generated.

Malignant pertussis is a severe infection in infants under 2 months, often leading to death. Current treatments are largely ineffective, highlighting the critical need for prevention strategies in young adults.

More Related Videos

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Related Experiment Videos

Last Updated: Jun 18, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Neonatology

Background:

  • Malignant pertussis poses a significant threat to young infants.
  • Early diagnosis and intervention are crucial for managing severe pertussis cases.

Observation:

  • Three infants under two months experienced severe pertussis requiring hospitalization.
  • Echocardiography revealed pulmonary hypertension in affected infants.
  • Standard treatments like high-frequency oscillations and nitric oxide failed to improve outcomes.

Findings:

  • All hospitalized infants experienced progressive respiratory and hemodynamic deterioration.
  • Exchange transfusion was unsuccessful in the third case.
  • Multiorgan failure led to the death of all three infants.

Implications:

  • Malignant pertussis is a leading cause of infectious mortality in neonates.
  • Current therapeutic strategies for severe pertussis in infants are often ineffective.
  • Prevention through vaccination of young adults is paramount to protect vulnerable infants.