Related Experiment Video
Updated: Jun 18, 2026
Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
The mammographic correlations with Basal-like phenotype of invasive breast cancer
Xiao Wang1, Lan Chao, Liansheng Chen
1Department of Breast Surgery, Jinan Central Hospital, Shandong University School of Medicine, Jinan 250013, China. wangxiao@sdu.edu.cn
Rationale And Objectives:
Mammography contributes to the improvement of breast carcinoma survival through early detection and treatment of breast lesions. The basal-like phenotype has been found to be an independent poor prognostic factor for breast cancer. The aim of this study was to determine the mammographic correlates of the basal-like phenotype of invasive breast cancer, and to more precisely predict patient outcome and those individuals who will be responsive to a specific therapeutic regimen.
Materials And Methods:
The mammographic findings in 267 patients with operable breast cancer were correlated with the basal-like subtype identified using immunohistochemical assessment of breast cancer cases, including estrogen receptor, progesterone receptor, HER-2/neu status, cytokeratin (CK5/6), and epidermal growth factor receptor.
Results:
Of the 267 invasive breast cancers, 40 (15%) were of the basal-like phenotype. Basal-phenotype tumors were significantly more likely to manifest as a mass (P = .002), most of which were indistinct margin (P =.035), at mammography, and architecture distortion at mammography (P = .002).
Conclusion:
The mammographic appearances of basal-like tumors, more mass and architecture distortion, suggest more rapid carcinogenesis. Additional studies are warranted to further refine prognosis, and to optimize treatment in patients with basal-like breast cancer.
