Related Experiment Video
Updated: Jun 18, 2026

Open-Source Miniature Fluorimeter to Monitor Real-Time Isothermal Nucleic Acid Amplification Reactions in Resource-Limited Settings
Published on: February 3, 2021
Development of a portable A-ABR screener using a microprocessor
Hyung Wook Noh1, Tak Hyung Lee, Jong Wook Kim
1Graduate Program in Biomedical Engineering, Yonsei University, Seoul, Korea. happy05@yuhs.ac
Insights
Early detection of infant hearing loss is crucial for speech development. A new automated auditory brainstem response (A-ABR) system offers a reliable method for identifying hearing impairment in newborns and infants.
Area of Science:
- Audiology
- Biomedical Engineering
- Neonatal Care
Background:
- Hearing loss is a common birth defect, often diagnosed late, hindering speech and language development.
- Early intervention is critical for optimal speech and language outcomes in hearing-impaired children.
- Auditory Brainstem Response (ABR) is a reliable diagnostic tool for early hearing loss detection.
Purpose of the Study:
- To develop and validate a portable, automated Auditory Brainstem Response (A-ABR) system for early hearing impairment detection in infants.
- To utilize the 'Fsp' method for distinguishing between normal and impaired hearing.
- To assess the system's accuracy in identifying hearing status.
Main Methods:
- Development of a battery-operated, portable automated auditory brainstem response (A-ABR) system.
- Application of the 'Fsp' method for hearing impairment detection.
- Partial validation of the A-ABR system's accuracy in a cohort of normal-hearing adults.
Main Results:
- A functional A-ABR system was developed for automated hearing impairment detection.
- The 'Fsp' method was employed to differentiate hearing statuses.
- Initial validation demonstrated the system's potential, with further testing required.
Conclusions:
- The developed A-ABR system shows promise for the early and automated detection of hearing impairment in neonates and infants.
- Timely diagnosis through A-ABR can facilitate early intervention, improving speech and language development.
- Further comprehensive validation studies are necessary to confirm the system's clinical efficacy.
Abstract:
Hearing loss is one of the most common birth defects among infants. Most hearing-impaired children are not diagnosed until one to three years of age, which is too late to treat for normal speech and language development. If hearing impairment is identified and treated in its early stage, a child's speech and language skills could be comparable to his or her normal-hearing peers. Auditory brain-stem response (ABR) is nowadays one of the most reliable diagnostic tools in the early detection of hearing impairment. In this study, we applied the 'Fsp' method to distinguish between normal and impaired hearing. We have developed a battery-operated portable automated auditory brainstem response (A-ABR) system that automatically detects hearing impairment in neonates or infants. We partially validated the accuracy of this system in twenty normal-hearing adults.

