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Assessing systolic time-intervals from heart sound: a feasibility study
P Carvalho1, R P Paiva, R Couceiro
1Department of Informatics Engineering, Science and Technology Faculty of the University of Coimbra, Pólo II, Coimbra, Portugal. carvalho@dei.uc.pt
Summary
Heart sound analysis shows potential for accurately measuring key systolic time intervals. This non-invasive method estimates left ventricular ejection time (LVET) and pre-ejection period (PEP), crucial for assessing cardiac function.
Area of Science:
- Biomedical Engineering
- Cardiology
- Signal Processing
Background:
- Systolic time intervals (STI) are vital indicators of cardiac function.
- Accurate measurement of STI, specifically pre-ejection period (PEP) and left ventricular ejection time (LVET), is clinically significant.
- Current methods may be invasive or require specialized equipment.
Purpose of the Study:
- To investigate the feasibility of using heart sound (HS) to accurately determine aortic valve events.
- To establish heart sound analysis as a viable method for estimating PEP and LVET.
- To correlate heart sound-derived timings with echocardiography for validation.
Main Methods:
- Development of a heart sound (HS) model to identify aortic valve opening and closing moments.
- Extraction of distinct features from heart sounds to mark critical systolic timings.
- Comparative analysis of HS-derived PEP and LVET with simultaneous echocardiography recordings from 17 subjects.
Main Results:
- The proposed HS model successfully identified key moments in the cardiac cycle.
- Features derived from heart sounds provided clear markers for aortic valve events.
- HS-based estimations of LVET and PEP showed high correlation with echocardiography findings.
Conclusions:
- Heart sound analysis is a feasible and accurate method for estimating systolic time intervals.
- This non-invasive technique offers a promising alternative for routine cardiac function assessment.
- Further research can refine HS analysis for broader clinical application in cardiology.
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