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Related Experiment Video

Updated: Jun 18, 2026

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa
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Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Published on: September 27, 2018

Implantable functional gastrointestinal neurostimulation.

A S Jurkov1, A Arriagada, M P Mintchev

  • 1Department of Electrical and Computer Engineering, University of Calgary, Calgary, AB T2N 1N4 Canada. asdzhurk@ucalgary.ca

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|December 8, 2009
PubMed
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Neural Gastrointestinal Electrical Stimulation (NGES) accelerates gastric emptying and induces controlled contractions for treating motility disorders and obesity. This novel neurostimulation method shows promise in animal and human studies.

Area of Science:

  • Biomedical Engineering
  • Gastroenterology
  • Neuroscience

Background:

  • Gastric and colonic motor dysfunctions present significant health challenges.
  • Existing treatments for motility disorders and obesity have limitations.
  • Novel approaches are needed to modulate gastrointestinal motility.

Purpose of the Study:

  • To introduce and evaluate Neural Gastrointestinal Electrical Stimulation (NGES) as a novel method for controlling gastrointestinal contractions.
  • To assess the efficacy of NGES in treating gastric and colonic motility disorders.
  • To explore the potential of NGES for managing obesity.

Main Methods:

  • Development of a microprocessor-based neurostimulator generating multi-channel, high energy, high frequency waveforms.

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Related Experiment Videos

Last Updated: Jun 18, 2026

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa
08:17

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Published on: September 27, 2018

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals
08:26

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals

Published on: February 24, 2012

  • Application of NGES to the lower stomach and colon in acute animal and human tests, and chronic animal studies.
  • Evaluation of NGES effects on gastric emptying and colonic contractility.

    • Main Results:

    • NGES successfully accelerated gastric emptying of liquids and solids in experimental tests.
    • The technique demonstrated the ability to produce strong, externally-controlled retrograde contractions in the stomach and colon.
    • Acute and chronic tests confirmed the efficacy of NGES in animal models and human subjects.

    Conclusions:

    • Neural Gastrointestinal Electrical Stimulation (NGES) is a viable technique for modulating gastrointestinal motility.
    • NGES offers therapeutic potential for gastric motor dysfunctions, obesity, and severe constipation.
    • Further research and clinical translation of NGES are warranted.