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Updated: Jun 18, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Automated control of blood glucose in the OR and surgical ICU
Jason J Hsu1, Joseph I Wang, Amy Lee
1Johns Hopkins University Department of Biomedical Engineering and The Johns Hopkins Bayview Medical Center Department of Surgery, Baltimore, MD 21218, USA. jason.hsu@jhu.edu
Abstract:
A device which integrates existing intravenous continuous glucose monitors and infusion pumps into a central hub for automated intravenous intensive insulin therapy, targeting non-diabetic critically-ill patients is presented. Additionally, a fuzzy logic based controller that is capable of automatically making closed-loop decisions to achieve tight glycemic control between a euglycemic range of 90 to 120 mg/dl is presented. Initial bench top testing shows a significant improvement in glycemic control with fuzzy logic control when compared to manual infusion protocols currently used in hospitals; future animal testing will be performed to verify these results in vivo.
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