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Related Experiment Video

Updated: Jun 18, 2026

Low-Cost Electroencephalographic Recording System Combined with a Millimeter-Sized Coil to Transcranially Stimulate the Mouse Brain In Vivo
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Low-Cost Electroencephalographic Recording System Combined with a Millimeter-Sized Coil to Transcranially Stimulate the Mouse Brain In Vivo

Published on: May 26, 2023

A flexible microelectrode for mouse EEG.

Jee Hyun Choi1, Klaus Peter Koch, Wigand Poppendieck

  • 1Korea Institute of Science & Technology, Seoul 136-791 Republic of Korea and Department of Neuroscience, University of Science & Technology, Daejon 305-333 Korea. jeechoi@kist.re.kr

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|December 8, 2009
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel, lightweight polyimide microelectrode for multi-channel electroencephalography (EEG) in freely moving mice. This flexible device enables non-invasive brain monitoring under genetic manipulation.

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Last Updated: Jun 18, 2026

Low-Cost Electroencephalographic Recording System Combined with a Millimeter-Sized Coil to Transcranially Stimulate the Mouse Brain In Vivo
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High-density EEG Recordings of the Freely Moving Mice using Polyimide-based Microelectrode
06:59

High-density EEG Recordings of the Freely Moving Mice using Polyimide-based Microelectrode

Published on: January 11, 2011

High-density Electroencephalographic Acquisition in a Rodent Model Using Low-cost and Open-source Resources
12:39

High-density Electroencephalographic Acquisition in a Rodent Model Using Low-cost and Open-source Resources

Published on: November 26, 2016

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Materials Science

Background:

  • Electroencephalography (EEG) is crucial for monitoring brain states in mice, especially during genetic or molecular studies.
  • Existing methods can be invasive or restrictive for freely moving subjects.

Purpose of the Study:

  • To introduce a novel, flexible, and biocompatible microfabricated electrode for multi-channel mouse brain EEG recording.
  • To provide a lightweight and minimally invasive solution for long-term brain activity monitoring.

Main Methods:

  • Fabrication of a 32-channel polyimide-based microelectrode array with integrated connectors.
  • Assessment of electrode weight (under 150 mg) and implantation procedure (non-invasive).
  • Simultaneous EEG recording comparison with conventional screw electrodes.

Main Results:

  • The microelectrode successfully recorded broad-band EEG signals from the mouse skull.
  • The device is lightweight, flexible, and requires minimal surgical intervention for implantation.
  • Simultaneous recordings confirmed the efficacy of the novel microelectrode compared to traditional methods.

Conclusions:

  • The developed polyimide microelectrode offers a significant advancement for multi-channel EEG in freely moving mice.
  • This technology facilitates advanced neuroscience research by enabling robust brain state monitoring under various experimental conditions.