Related Experiment Video
Updated: Jun 18, 2026

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design
Published on: December 3, 2020
Monitoring blood oxygenation changes due to acute pain stimuli using functional near-infrared spectroscopy (fNIRS)
1School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104 USA. arezou@drexel.edu
Abstract:
We've used Near-Infrared Spectroscopy (fNIRS) as a noninvasive tool to monitor blood oxygenation due to the acute pain stimuli. The aim of the study was to find a relationship between the signals recorded by activation of the anterior cingulated cortex (ACC) in healthy subjects, who experience pain via stimulation, and the subject reported pain. These findings will shed light on pain related cognitive studies. Based on our findings, we believe that the fNIRS can be used as a tool for monitoring pain in the brain as well as an effective tool for monitoring the objective efficiency of the pain treatments. Results have shown a correlation between the fNIRS signal and patients' subjective pain level (mild, moderate and severe) which is evidence that the fNIRS is a useful tool for monitoring objective pain response.
