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Updated: Jun 18, 2026

Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
Comparative analysis of three different modalities for characterization of the seismocardiogram
Alireza Akhbardeh1, Kouhyar Tavakolian, Viatcheslav Gurev
1Computational and Electrophysiology lab, Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, 3400 N. Charles Street, CSEB Room 216, Baltimore, MD 21218, USA. akhbardeh@jhu.edu
Abstract:
We introduce and compare three different modalities to study seismocardiogram (SCG) and its correlation with cardiac events. We used an accelerometer attached to the subject sternum to get a reference measure. Cardiac events were then approximately identified using echocardiography. As an alternative approximation, we used consecutive Cine-MRI images of the heart to capture cardiac movements and compared them with the experimental SCG. We also employed an anatomically accurate, finite element base electromechanical model with geometry built completely from DT-MRI to simulate a portion of the cardiac cycle as observed in the SCG signal. The preliminary results demonstrate the usability of these newly proposed methods to investigate the mechanism of SCG waves and also demonstrate the usability of echocardiograph in interpretation of these results in terms of correlating them to underlying cardiac cycle events.
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