Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimating shear wave speeds and shear viscosities with a viscoelastic time-domain method.

The Journal of the Acoustical Society of America·2026
Same author

Optimizing imbalanced learning with genetic algorithm.

Scientific reports·2025
Same author

Scene flow based deep network for hand reconstruction using depth images.

Scientific reports·2025
Same author

Fast and Accurate Plane Wave and Color Doppler Imaging with the FOCUS Software Package.

Sensors (Basel, Switzerland)·2025
Same author

Three-dimensional time-domain Green's functions and spatial impulse responses for the van Wijngaarden wave equation.

The Journal of the Acoustical Society of America·2023
Same author

Numerical spatial impulse response calculations for a circular piston radiating in a lossy medium.

The Journal of the Acoustical Society of America·2022

Related Experiment Video

Updated: Jun 18, 2026

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats
09:36

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

Published on: March 23, 2022

Automated PET/CT brain registration for accurate attenuation correction.

Khawar Khurshid, Kevin L Berger, Robert J McGough

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 8, 2009
    PubMed
    Summary

    Patient motion can cause misalignment in brain PET/CT scans, leading to inaccurate attenuation correction. Automated software was developed to register PET and CT images, correcting artifacts and improving diagnostic accuracy for brain imaging.

    More Related Videos

    Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images
    09:21

    Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

    Published on: February 18, 2015

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
    07:57

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

    Published on: March 24, 2022

    Related Experiment Videos

    Last Updated: Jun 18, 2026

    In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats
    09:36

    In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

    Published on: March 23, 2022

    Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images
    09:21

    Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

    Published on: February 18, 2015

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
    07:57

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

    Published on: March 24, 2022

    Area of Science:

    • Medical Imaging
    • Nuclear Medicine
    • Radiology

    Background:

    • Computed Tomography (CT) is crucial for Positron Emission Tomography (PET) attenuation correction, enhancing data acquisition and improving reconstructed PET image quality in brain studies.
    • Misalignment between PET and CT images is a significant challenge, primarily caused by patient motion during or between scans.
    • Image misregistration leads to erroneous CT attenuation maps, potentially causing under- or over-estimation of attenuation and diagnostic misinterpretation.

    Purpose of the Study:

    • To develop automated software for accurate PET/CT brain registration.
    • To eliminate misregistration artifacts and potential diagnostic errors in brain PET/CT imaging.
    • To improve the quality and reliability of PET/CT brain scans.

    Main Methods:

    • Development of automated software for PET/CT brain registration.
    • Extraction of brain surface information from both CT and PET images.
    • Compensation for translational and rotational misalignments between PET and CT scans.

    Main Results:

    • The developed software successfully registered PET and CT images, correcting for misalignment.
    • Application to a patient dataset with a visible perfusion defect demonstrated artifact elimination.
    • The corrected CT attenuation map (CTAC) resolved hypoperfusion artifacts caused by erroneous PET attenuation.

    Conclusions:

    • Automated PET/CT brain registration software effectively corrects misregistration artifacts.
    • The improved CTAC enhances the diagnostic accuracy of brain PET/CT imaging.
    • This technology is vital for reliable interpretation of brain perfusion studies.