Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Frequency of the vertical cup-to-disc ratio to normal optical disc size.

Archivos de la Sociedad Espanola de Oftalmologia·2025
Same author

Neglect what is near. Commentary regarding the August 2021 editorial on the current state of Artificial Intelligence in Ophthalmology.

Archivos de la Sociedad Espanola de Oftalmologia·2022
Same author

Evolution and associated factors of hand hygiene compliance in a pediatric tertiary hospital.

American journal of infection control·2020
Same author

[Evolution of treatment of syphilis through history].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2018
Same author

Physiological and metabolic responses in newborn piglets associated with the birth order.

Animal reproduction science·2018
Same author

Combined spatial, contrast, and temporal functions perimetry in mild glaucoma and ocular hypertension.

European journal of ophthalmology·2017

Related Experiment Video

Updated: Jun 18, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Detection of morphological and functional progression in initial glaucoma.

M Gonzalez de la Rosa1, M Gonzalez-Hernandez, M Sanchez-Mendez

  • 1The Hospital Universitario de Canarias, La Laguna, Spain. mgdelarosa@telefonica.net

The British Journal of Ophthalmology
|December 8, 2009
PubMed
Summary
This summary is machine-generated.

Functional indices, particularly Pulsar, demonstrated superior glaucoma progression detection compared to morphological methods in a prospective study. This finding aids in earlier and more accurate diagnosis of visual field defects.

More Related Videos

In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma
12:48

In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma

Published on: May 11, 2015

Related Experiment Videos

Last Updated: Jun 18, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma
12:48

In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma

Published on: May 11, 2015

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Visual Neuroscience

Background:

  • Glaucoma diagnosis and monitoring are critical for preventing vision loss.
  • Early detection of glaucoma progression is essential for timely intervention.
  • Evaluating functional and morphological imaging data aids in glaucoma management.

Purpose of the Study:

  • To prospectively assess functional and morphological data for glaucoma progression.
  • To compare the diagnostic capabilities of various imaging and perimetry techniques.
  • To identify the most sensitive methods for detecting early glaucoma changes.

Main Methods:

  • Prospective follow-up of 156 eyes with early, moderate, or suspected glaucoma over 3.6 years.
  • Utilized Heidelberg retinal tomograph, laser polarimetry, and standard, Pulsar, and frequency doubling technology perimetries.
  • Employed regression analysis and the threshold noiseless trend (TNT) program for progression estimation.

Main Results:

  • Threshold noiseless trend (TNT) perimetry, especially with Pulsar, showed over twice the diagnostic capacity.
  • TNT Pulsar identified progression in 40% of cases after seven examinations with high confirmation rates.
  • Morphological methods (Heidelberg retinal tomograph, laser polarimetry) had limited diagnostic yield for progression.

Conclusions:

  • Functional indices, particularly Pulsar perimetry, offer superior detection of glaucoma progression compared to morphological indices.
  • Threshold noiseless trend (TNT) analysis enhances the sensitivity of functional assessments.
  • Low diagnostic agreement between methods highlights the need for complementary approaches in glaucoma monitoring.