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Updated: Jun 18, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Two novel bis-azomethines derived from quinoxaline-2-carbaldehyde
Digna Varghese1, V Arun, P P Robinson
1Department of Applied Chemistry, Cochin University of Science and Technology, Cochin 682 022, Kerala, India.
Abstract:
The Schiff base compounds N,N'-bis[(E)-quinoxalin-2-ylmethylidene]propane-1,3-diamine, C(21)H(18)N(6), (I), and N,N'-bis[(E)-quinoxalin-2-ylmethylidene]butane-1,4-diamine, C(22)H(20)N(6), (II), crystallize in the monoclinic crystal system. These molecules have crystallographically imposed symmetry. Compound (I) is located on a crystallographic twofold axis and (II) is located on an inversion centre. The molecular conformations of these crystal structures are stabilized by aromatic pi-pi stacking interactions.
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