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Utilizing Thermal Shift Assay to Probe Substrate Binding to Selenoprotein O
Published on: August 9, 2024
Selenocysteine is selectively taken up by red blood cells
Takeshi Imai1, Hisaaki Mihara, Tatsuo Kurihara
1Institute for Chemical Research, Kyoto University, Uji, Japan.
Bioscience, Biotechnology, and Biochemistry
|December 8, 2009
Abstract:
Both organic and inorganic forms of selenium are utilized in the biosynthesis of selenoproteins. Selenite is taken up by red blood cells and then returned to the plasma after reduction, but little is known about the metabolic fate of selenocysteine. We found that selenocysteine was taken up into red blood cells without decomposition into selenide.
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