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Updated: Jun 18, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
Published on: June 26, 2020
[A case of HIV coinfected with hepatitis B virus treated by entecavir]
Akihiro Yamada1, Akahito Sako, So Nishimura
1Division of Gastroenterology, Toyama Hospital, International Medical Center of Japan, Japan. akihiyamada-gi@umin.ac.jp
Abstract:
A 45-year-old male active homosexual was given a diagnosis of HIV-1 and acute hepatitis B in August 2007. Since his liver function became rapidly impaired, anti-HBV therapy with oral administration of entecavir (ETV) was started, and resulted in a favorable outcome. However, serum concentration of HIV-RNA decreased by log 1.26 within 60 days, which strongly suggested the inhibition of HIV proliferation by ETV. To prevent the appearance of mutated HIV, novel therapeutic strategies should be established in HIV/HBV-coinfected patients.
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