Related Experiment Video
Updated: Jun 18, 2026
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
Published on: April 25, 2025
Lacrimal obstruction in inflammatory bowel disease
1Orbital Plastic and Lacrimal Clinic, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
This study found a higher rate of inflammatory bowel disease (IBD) in patients with acquired lacrimal obstruction. Further investigation, including lacrimal sac biopsies, is recommended for patients with IBD undergoing dacryocystorhinostomy.
Area of Science:
- Ophthalmology
- Gastroenterology
- Inflammatory Bowel Disease
Background:
- Acquired lacrimal obstruction is a common condition requiring surgical intervention.
- Inflammatory bowel disease (IBD) encompasses chronic conditions affecting the digestive tract.
- The association between IBD and lacrimal drainage obstruction is not well-established.
Purpose of the Study:
- To investigate the prevalence of IBD in patients presenting with acquired lacrimal obstruction.
- To determine if there is a statistically significant association between IBD and lacrimal drainage issues.
Main Methods:
- Retrospective review of 461 adult patients undergoing dacryocystorhinostomy for acquired lacrimal obstruction.
- Identification of patients with a diagnosis of IBD.
- Collection of data on secondary causes, sinonasal disease, and surgical outcomes.
Main Results:
- Nine patients (1.7%) were identified with IBD (Crohn disease or ulcerative colitis).
- Seven patients had nasolacrimal duct stenosis/obstruction; two had canalicular obstruction.
- The prevalence of IBD in this cohort was significantly higher than the general Australian population (0.3%, p < 0.0001).
Conclusions:
- A higher-than-expected rate of IBD was observed in patients with acquired lacrimal obstruction.
- The findings suggest a potential association between IBD and lacrimal drainage issues.
- Lacrimal sac biopsies in IBD patients undergoing dacryocystorhinostomy are recommended for further research.
More Related Videos
07:30Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction
Published on: October 13, 2017
08:04A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
Published on: January 24, 2020
Related Concept Videos
01:30Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
01:21Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
01:25Inflammatory Bowel Disease III: Crohn's Disease
01:26Inflammatory Bowel Disease I: Introduction
01:20Inflammatory Bowel Disease II: Ulcerative Colitis
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...