Related Experiment Video
Updated: Jun 18, 2026
08:13
In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation
Published on: November 11, 2025
Acne agminata limited to the eyelids
Alan D Proia1, Michael J Richard
1Department of Pathology and daggerOphthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA. proia001@mc.duke.edu
Ophthalmic Plastic and Reconstructive Surgery
|December 8, 2009
Summary
Acne agminata, a rare facial inflammation, presents as small papules on eyelids. This condition, also known as lupus miliaris disseminatus faciei, requires differential diagnosis from other skin conditions.
Area of Science:
- Dermatology
- Ophthalmology
Background:
- Acne agminata, also termed lupus miliaris disseminatus faciei, is a rare necrotizing granulomatous dermatitis.
- This condition is infrequently discussed in ophthalmologic literature, highlighting a knowledge gap.
Observation:
- A 45-year-old woman presented with a year-long history of small, fluctuating papules on her upper eyelids.
- Notably, these papules resolved near a site of prior steroid injection.
Findings:
- Acne agminata is characterized by necrotizing granulomatous inflammation of the dermis.
- Diagnosis relies on excluding other granulomatous dermatitis forms through clinical and histological examination.
Implications:
- Increased awareness of acne agminata in ophthalmology is warranted.
- Understanding its presentation and diagnostic criteria can improve patient management.
More Related Videos
Related Concept Videos
01:27Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
01:22Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
01:21Accessory Structures of the Skin: Sebaceous Glands
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
01:17Accessory Structures of the Eye
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...