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465
Myxoid neurofibroma: an unusual presentation
Rosa Maria Ponce-Olivera1, Andres Tirado-Sanchez, Amelia Peniche-Castellanos
1Service of Dermatology, Hospital General de México.
Indian Journal of Dermatology
|December 8, 2009
Summary
Myxoid neurofibroma (MN), a benign tumor of perineural cell origin, is typically found on the face and limbs. This report details the first known case of an MN located on the trunk, expanding its differential diagnosis.
Area of Science:
- Oncology
- Dermatopathology
- Surgical Pathology
Background:
- Myxoid neurofibroma (MN) is a rare, benign tumor originating from perineural cells.
- Immunohistochemical staining for S-100 protein is a key diagnostic marker for MN.
- Commonly observed locations include the face, shoulders, arms, periungual areas, and feet.
Purpose of the Study:
- To report the first documented case of a myxoid neurofibroma occurring on the trunk.
- To emphasize the importance of considering MN in the differential diagnosis of trunk tumors.
Main Methods:
- Case report detailing a tumor on the trunk.
- Histopathological examination and immunohistochemical analysis (S-100 protein staining).
Main Results:
- The tumor exhibited characteristics consistent with myxoid neurofibroma.
- Immunohistochemistry confirmed positive S-100 protein expression.
- The location on the trunk is unprecedented in existing literature.
Conclusions:
- Myxoid neurofibroma can occur in unusual locations, such as the trunk.
- Clinicians should consider myxoid neurofibroma in the differential diagnosis of trunk masses.
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