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Updated: Jun 18, 2026
Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
[Development of tumor treatment-related premature ovarian failure and ovarian function reconstruction]
Objective:
To analyze the reason of tumor treatment-related premature ovarian failure, and to review the progress of ovarian functional reconstruction.
Methods:
The literature about the effects of radiotherapy and chemotherapy on ovarian function and reconstruct ovarian function was reviewed, analysed and summarized.
Results:
Radiotherapy and chemotherapy can both affect ovarian function. The ovarian function reconstruction included fresh ovarian transplantation and ovarian cryopreservation and transplantation. Frequent ovarian cryopreservation was procedure slow-freezing protocols and vitrification protocols. Some laboratory and animal models of ovarian function reconstruction have come to gratifying results.
Conclusion:
Ovarian function reconstruction has a potential clinical value and provides a promising future.
