Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Variability in thrombolytic practice in Oregon.

G P Young1, J R Hedges, J L Collings

  • 1Division of Emergency Medicine, Oregon Health Sciences University, Portland.

Annals of Emergency Medicine
|March 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Circulating tumour DNA and MRI circumferential resection margin are key prognostic indicators for survival in rectal cancer.

ESMO gastrointestinal oncology·2026
Same author

Definition and taxonomy of interval colorectal cancers: a proposal for standardising nomenclature.

Gut·2014
Same author

An updated Asia Pacific Consensus Recommendations on colorectal cancer screening.

Gut·2014
Same author

Colorectal disorders: A dietary management perspective.

Asia Pacific journal of clinical nutrition·2014
Same author

Prevention of colon cancer: role of short chain fatty acids produced by intestinal flora.

Asia Pacific journal of clinical nutrition·2014
Same author

Treatment of rheumatic disorders. 1912.

The Practitioner·2012
Same journal

Variation in Emergency Department Experience With Pediatric Critical Illness.

Annals of emergency medicine·2026
Same journal

Point-of-Care Ultrasound-Guided Hydrostatic Reduction of Ileocolic Intussusception in the Pediatric Emergency Department.

Annals of emergency medicine·2026
Same journal

Managing Diabetic Ketoacidosis.

Annals of emergency medicine·2026
Same journal

Needle Thoracostomy: Implications of Chest Wall Thickness for Anatomical Location and Needle Length.

Annals of emergency medicine·2026
Same journal

Women Emergency Physicians and Gender Disparities from Entry to Advancement.

Annals of emergency medicine·2026
Same journal

Policy Statements Approved March 2026.

Annals of emergency medicine·2026
See all related articles

Oregon emergency departments show significant variability in thrombolytic protocols for patient care. This study highlights inconsistencies in therapy initiation, evaluation, and available agents, impacting emergency medicine practices.

Area of Science:

  • Emergency Medicine
  • Cardiology
  • Pharmacology

Background:

  • Thrombolytic therapy is crucial for acute cardiovascular events.
  • Standardized protocols are essential for effective and safe administration in emergency settings.

Purpose of the Study:

  • To assess current thrombolytic protocols in Oregon emergency departments.
  • To identify variations in patient evaluation, inclusion/exclusion criteria, therapy initiation, and available thrombolytic agents.

Main Methods:

  • A telephone survey was conducted among head nurses in Oregon's acute-care hospital emergency departments (EDs).
  • Sixty-seven out of 70 contacted hospitals (96%) participated, with 61 (87%) having written protocols for thrombolytic agent use.
  • Data on protocol specifics were compared using the Kruskal-Wallis test.

Related Experiment Videos

Main Results:

  • Significant variability exists in how thrombolytic therapy is initiated, with emergency physician discretion being the most common method (32%).
  • Electrocardiogram interpretation before drug administration varies among emergency physicians, cardiologists, and computer systems.
  • Both tissue plasminogen activator (tPA) and streptokinase are available in most hospitals (75%), but their exclusive use and ED administration sites differ.
  • ED administration of thrombolytics correlated with the number of full-time emergency physicians and board-certified specialists.

Conclusions:

  • Thrombolytic protocols demonstrate high variability across Oregon EDs.
  • Inconsistencies in protocols may affect the timely and appropriate use of thrombolytic agents.