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Published on: December 2, 2015
Depression and related psychological factors in heart disease
Laura K Kent1, Peter A Shapiro
1Department of Psychiatry, Columbia University/New York State Psychiatric Institute, New York, NY 10032, USA. lk2129@columbia.edu
Insights
Depression and psychological factors significantly increase heart disease risk. Effective treatments for depression in heart disease patients are supported by clinical trials, improving patient outcomes.
Area of Science:
- Cardiology
- Psychiatry
- Psychosomatic Medicine
Background:
- Heart disease is prevalent in patients with depression.
- Epidemiological studies show clear links between depression and heart disease in various populations.
- Psychological factors like vital exhaustion, Type A behavior, anger, hostility, and Type D personality are associated with heart disease.
Purpose of the Study:
- To review the role of depression and related psychological factors in heart disease.
- To summarize proposed mechanisms linking negative affect to heart disease.
- To review current treatments for depression in heart disease patients.
Main Methods:
- Literature review of epidemiological studies.
- Review of research on psychological factors and heart disease.
- Analysis of clinical trial data on depression treatment in cardiac patients.
Main Results:
- High prevalence of heart disease in depressed individuals.
- Established epidemiological links between depression and heart disease.
- Evidence supports various treatment strategies for depression in heart disease.
Conclusions:
- Depression and psychological distress are significant risk factors for heart disease.
- Understanding the mechanisms linking psychological factors to heart disease is crucial.
- Treatment of depression is an important component in managing heart disease patients.
Abstract:
In this article we review the role of depression and other related psychological factors in heart disease. The prevalence of heart disease in patients with depression is high, and epidemiological links between depression and heart disease are evident in studies of community samples, psychiatric patients, and heart disease patients. We also describe the links between heart disease and related psychological factors-including vital exhaustion, Type A behavior pattern, anger and hostility, and Type D personality-and summarize proposed mechanisms that may link negative affects with heart disease. Finally, we review treatment of depression in heart disease, including evidence from several large clinical trials.
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