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Apparent response of subacute sclerosing panencephalitis to intrathecal interferon alpha
M Miyazaki1, T Hashimoto, K Fujino
1Department of Pediatrics, University of Tokushima, School of Medicine, Japan.
Annals of Neurology
|January 1, 1991
Abstract:
An 8-year-old boy with subacute sclerosing panencephalitis (SSPE) was treated with 1.0 to 3.0 x 10(6) IU human interferon alpha (IFN) by the intrathecal route weekly or fortnightly. Pronounced improvement of clinical and electroencephalographic findings were observed in a dose-dependent manner. Our patient raises hope that IFN can induce sustained remission in patients with SSPE.