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Updated: Jun 18, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Reference values for N-terminal pro-B-type natriuretic peptide in fetal circulation between 20 and 34 weeks of
Waltraut M Merz1, Kirsten Kübler, Eike Albers
1Department of Obstetrics and Prenatal Medicine, University of Bonn Medical School, Sigmund-Freud-Str. 25, D-53105 Bonn, Germany. Waltraut.Merz@ukb.uni-bonn.de
Objective:
We aimed to investigate the range of fetal NT-proBNP values in normal pregnancy between 20 and 34 weeks of gestation.
Method:
NT-proBNP was measured in 56 fetal blood samples.
Results:
Mean (+ or - 2 SD) NT-proBNP concentration was 1998 (242-3754) ng/L; a significant decline occurred with advancing gestational age (p=0.012).
Conclusions:
Gestational age has to be taken in to consideration in the assessment of NT-proBNP. Our data may be used as reference values in fetal and neonatal medicine.
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