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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Functionally graded hydroxyapatite coatings doped with antibacterial components
Xiao Bai1, Karren More, Christopher M Rouleau
1Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695, USA.
Acta Biomaterialia
|December 9, 2009
Summary
Functionally graded hydroxyapatite (FGHA) coatings with silver nanoparticles were developed on titanium. These silver-infused FGHA coatings demonstrated strong adhesion, comparable to non-silvered coatings, indicating potential for biomedical applications.
Area of Science:
- Biomaterials Science
- Materials Engineering
- Nanotechnology
Background:
- Titanium implants are widely used in orthopedics and dentistry.
- Hydroxyapatite (HA) coatings enhance osseointegration of titanium implants.
- Incorporating silver into HA coatings may provide antimicrobial properties.
Purpose of the Study:
- To develop silver-incorporated functionally graded hydroxyapatite (FGHA) coatings on titanium substrates.
- To characterize the structural, compositional, and adhesion properties of these FGHA coatings.
- To evaluate the effect of silver incorporation on the coating's adhesion strength.
Main Methods:
- Ion beam-assisted deposition was used to create FGHA coatings with varying silver percentages on titanium.
- Transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM) with energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) were employed for characterization.
- Pull-off tests were conducted to evaluate the adhesion strength of the coatings.
Main Results:
- TEM and STEM-EDS confirmed the presence of nanoscale silver particles distributed throughout the FGHA coatings.
- XRD and TEM analysis verified the presence of hydroxyapatite within the coatings.
- Surface silver content ranged from 1.09 to 6.59 wt.%, approximately half of the bulk concentration.
- Adhesion strengths were measured between 83+/-6 MPa and 88+/-3 MPa, comparable to silver-free FGHA (85 MPa).
- The primary failure mode observed in adhesion tests was epoxy failure, not coating delamination.
Conclusions:
- Silver-incorporated FGHA coatings can be successfully fabricated on titanium substrates using ion beam-assisted deposition.
- The incorporation of silver does not compromise the adhesion strength of FGHA coatings on titanium.
- The observed distribution of silver nanoparticles and strong adhesion suggest potential for these coatings in antimicrobial implant applications.
