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Updated: Jun 18, 2026
Synthesis and Characterization of Amphiphilic Gold Nanoparticles
Published on: July 2, 2019
Hydrothermal synthesis of histidine-functionalized single-crystalline gold nanoparticles and their pH-dependent UV
Zhiguo Liu1, Yuangang Zu, Yujie Fu
1Key Laboratory of Forest Plant Ecology of Ministry of Education, Northeast Forestry University, Harbin, China.
Abstract:
L-Histidine capped single-crystalline gold nanoparticles have been synthesized by a hydrothermal process under a basic condition at temperature between 65 and 150 degrees C. The produced gold nanoparticles were spherical with average diameter of 11.5+/-2.9nm. The synthesized gold colloidal solution was very stable and can be stored at room temperature for more than 6 months. The color of the colloidal solution can change from wine red to mauve, purple and blue during the acidifying process. This color changing phenomenon is attributed to the aggregation of gold nanoparticles resulted from hydrogen bond formation between the histidines adsorbed on the gold nanoparticles surfaces. This hydrothermal synthetic method is expected to be used for synthesizing some other amino acid functionalized gold nanomaterials.
