Related Experiment Video
Updated: Jun 18, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Real-time three-dimensional echocardiographic left ventricular systolic assessment: side-by-side comparison with
Marcelo L C Vieira1, César H Nomura, Bernardino Tranchesi
1Echocardiography Sector, Hospital Israelita Albert Einstein, R. Cardoso de melo, 463, apt 21, Vila Olímpia, São Paulo 04548-002, Brazil. mluiz766@terra.com.br
Insights
Real-time 3D echocardiography (RT3DE) and cardiac computed tomography (CCT) show strong correlation in assessing left ventricular ejection fraction (LVEF) and volumes. These imaging techniques provide comparable results for evaluating cardiac function and geometry.
Area of Science:
- Cardiovascular Imaging
- Medical Diagnostics
- Echocardiography and CT
Background:
- Accurate assessment of left ventricular systolic function and geometry is crucial for diagnosing and managing cardiovascular diseases.
- Real-time 3D echocardiography (RT3DE) and cardiac computed tomography (CCT) are advanced imaging modalities with the potential to provide detailed cardiac information.
Purpose of the Study:
- To compare the accuracy of RT3DE and CCT in analyzing left ventricle ejection fraction (LVEF) and volumes.
- To investigate the correlation between RT3DE and CCT measurements of cardiac function and geometry.
Main Methods:
- Prospective study of 67 patients (37 males, mean age 55 years).
- Patients underwent both RT3DE and 64-slice CCT examinations.
- Analysis of LVEF, left ventricular end-diastolic volume (LVEDV), and left ventricular end-systolic volume (LVESV) using both modalities.
Main Results:
- Strong correlations were found between RT3DE and CCT for LVEF (r=0.79, P<0.0001), LVEDV (r=0.82, P<0.0001), and LVESV (r=0.91, P<0.0001).
- RT3DE LVEF ranged from 30-78.6% (mean 63.1±7.33%), LVEDV from 44.1-210 mL (mean 104.9±29.7 mL), and LVESV from 11.4-149 mL (mean 38.9±19.3 mL).
- CCT LVEF ranged from 28-86% (mean 66±8.4%), LVEDV from 51-212 mL (mean 110.3±31.2 mL), and LVESV from 7-152 mL (mean 38.2±19.2 mL).
Conclusions:
- RT3DE and CCT demonstrate adequate correlation in assessing ventricular systolic function and geometry.
- Both imaging techniques are reliable for evaluating left ventricular parameters.
Aims:
To investigate by real-time 3D echocardiography (RT3DE) and cardiac computed tomography (CCT) the analysis of left ventricle ejection fraction (LVEF) and volumes.
Methods And Results:
A total of 67 patients (37 males, 55 +/- 11 years) were studied prospectively by RT3DE and by 64-slice CCT. RT3DE data: LVEF ranged from 30 to 78.6% (63.1 +/- 7.33); left ventricular end-diastolic volume (LVEDV) from 44.1 to 210 (104.9 +/- 29.7) mL; left ventricular end-systolic volume (LVESV) from 11.4 to 149 ( 38.9 +/- 19.3) mL. CCT data: LVEF ranged from 28 to 86% (66 +/- 8.4); LVEDV from 51 to 212 (110.3 +/- 31.2) mL; LVESV from 7 to 152 (38.2 +/- 19.2) mL. Correlations relative to RT3DE and CCT were: LVEF (r: 0.79, P < 0.0001); LVEDV (r: 0.82, P < 0.0001); and LVESV (r: 0.91, P < 0.0001).
Conclusion:
It was observed adequate correlation between RT3DE and CCT ventricular systolic function and geometry assessment.
Related Concept Videos
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...

