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Establishment and Analysis of Tumor Slice Explants As a Prerequisite for Diagnostic Testing
11:00

Establishment and Analysis of Tumor Slice Explants As a Prerequisite for Diagnostic Testing

Published on: November 29, 2018

Selected items from the history of pathology: friedrich krukenberg and his tumor

W B Ober

    The American Journal of Pathology
    |December 9, 2009
    PubMed
    Abstract

    No abstract available in PubMed .

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    Tumor Progression

    Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
    Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

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