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[The relation between granulocyte elastase activity in cervical mucus and gestational cervical polyp].
1Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine.
Nihon Sanka Fujinka Gakkai Zasshi
|January 1, 1991
Summary
Pregnant women with cervical polyps have higher granulocyte elastase activity, a marker of inflammation. Removing these polyps significantly reduces elastase activity and lowers the risk of chorioamnionitis.
Area of Science:
- Obstetrics and Gynecology
- Inflammation Markers
- Cervical Pathology
Context:
- Cervical polyps are common in pregnant women.
- The role of cervical polyps in pregnancy complications is not fully understood.
- Granulocyte elastase is an inflammatory marker.
Purpose:
- To investigate elastase activity in cervical mucus of pregnant women with and without cervical polyps.
- To assess the effect of cervical polyp removal (polypectomy) on elastase activity.
- To evaluate the association between cervical polyps, elastase activity, and chorioamnionitis.
Summary:
- Pregnant women with cervical polyps exhibited significantly higher cervical mucus elastase activity compared to controls.
- Polypectomy led to a significant decrease in elastase activity.
- High elastase activity and the presence of polyps without removal were associated with an increased risk of chorioamnionitis.
Impact:
- Cervical polyps may act as a focus of inflammation during pregnancy.
- Cervical polyps are linked to an increased risk of chorioamnionitis.
- Surgical removal of cervical polyps during pregnancy is recommended to mitigate risks.