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Sinemet CR in Parkinson's disease
R F Pfeiffer1, K E Wilken, C S Glaeske
1University of Nebraska Medical Center, Section of Neurology, Omaha 68198-2045.
The Nebraska Medical Journal
|January 1, 1991
Abstract:
Sinemet CR, a controlled release carbidopa/levodopa preparation, was compared to conventional carbidopa/levodopa in a double blind, placebo-controlled trial. Comparable clinical benefits and adverse effects were noted with the two medications. However significantly less frequent dosing was necessary with Sinemet CR.